Opportunities for Combinatorial Optimization
نویسنده
چکیده
T his is a survey designed for mathematical programming people who do not know molecular biology and want to learn the kinds of combinatorial optimization problems that arise. After a brief introduction to the biology, we present optimization models pertaining to sequencing, evolutionary explanations, structure prediction, and recognition. Additional biology is given in the context of the problems, including some motivation for disease diagnosis and drug discovery. Open problems are cited with an extensive bibliography, and we offer a guide to getting started in this exciting frontier.
منابع مشابه
Winner Determination in Combinatorial Auctions using Hybrid Ant Colony Optimization and Multi-Neighborhood Local Search
A combinatorial auction is an auction where the bidders have the choice to bid on bundles of items. The WDP in combinatorial auctions is the problem of finding winning bids that maximize the auctioneer’s revenue under the constraint that each item can be allocated to at most one bidder. The WDP is known as an NP-hard problem with practical applications like electronic commerce, production manag...
متن کاملSelecting Efficient Service-providers in Electric Power Distribution Industry Using Combinatorial Reverse Auction
In this paper, a combinatorial reverse auction mechanism is proposed for selecting the most efficient service-providers for resolving sustained power interruptions in multiple regions of an electric power distribution company’s responsibility area. Through this mechanism, supplying the required service in each region is assigned to only one potential service-provider considering two criteria in...
متن کاملA hybrid metaheuristic using fuzzy greedy search operator for combinatorial optimization with specific reference to the travelling salesman problem
We describe a hybrid meta-heuristic algorithm for combinatorial optimization problems with a specific reference to the travelling salesman problem (TSP). The method is a combination of a genetic algorithm (GA) and greedy randomized adaptive search procedure (GRASP). A new adaptive fuzzy a greedy search operator is developed for this hybrid method. Computational experiments using a wide range of...
متن کاملOptimization of profit and customer satisfaction in combinatorial production and purchase model by genetic algorithm
Optimization of inventory costs is the most important goal in industries. But in many models, the constraints are considered simple and relaxed. Some actual constraints are to consider the combinatorial production and purchase models in multi-products environment. The purpose of this article is to improve the efficiency of inventory management and find the economic order quantity and economic p...
متن کاملAn optimization technique for vendor selection with quantity discounts using Genetic Algorithm
Vendor selection decisions are complicated by the fact that various conflicting multi-objective factors must be considered in the decision making process. The problem of vendor selection becomes still more compli-cated with the inclusion of incremental discount pricing schedule. Such hard combinatorial problems when solved using meta heuristics produce near optimal solutions. This paper propose...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2005